What does it really mean to change the game in energy technologies? Not to change a single game – as with a last-second shot at the buzzer, a Hail Mary pass, or a diving catch to close out the inning – but to transform the entire game, with new rules, new technologies, and often-unexpected new results.In the National Laboratory system, we are working on new energy technologies that could transform the ways we generate, store and use energy, and that could protect our environment while recharging our national economy. But as we tackle the fundamental scientific research we need to discover and develop disruptive new energy technologies, it’s worthwhile to ask: What does game-changing technology look like, and what are currently our best prospects for game changers?